Infantile hemangiomas are the most common benign vascular tumors in childhood.
Propranolol is the first‐line treatment for infantile hemangiomas, but failures may occur.
Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations
and vascular tumors. We present the case of a child with multiple infantile hemangiomasthat
was successfully treated with sirolimus and propranolol after failure of combined propranolol
and prednisolone treatment.