Patterns of infantile hemangiomas: new clues to hemangioma pathogenesis and embryonic facial development

AN Haggstrom, EJ Lammer, RA Schneider… - …, 2006 - publications.aap.org
OBJECTIVES. Large facial infantile hemangiomas have higher rates of complications than
small localized hemangiomas, more often require treatment, and can be associated with
neurological, ophthalmologic, and cardiac anomalies (PHACE syndrome). The anatomic
patterns of these hemangiomas are often referred to as “segmental” despite a lack of precise
anatomic definitions. Our study aims to define “segmental” hemangiomas based on clinically
observed patterns. Our secondary goal is to relate the observed patterns to currently …