Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillation

WC Winkelmayer, J Liu, S Setoguchi… - Clinical Journal of the …, 2011 - journals.lww.com
Results Among 2313 patients with new AF who survived 30 days from discharge, 249
(10.8%) filled a prescription for warfarin. Comparing 237 warfarin users and 948 propensity-
matched nonusers over 2287 person-years of follow-up, the occurrence of ischemic stroke
was similar (HR= 0.92; 95% CI, 0.61 to 1.37), whereas warfarin users experienced twice the
risk of hemorrhagic stroke (HR= 2.38; 95% CI, 1.15 to 4.96). The risks of stroke,
gastrointestinal hemorrhage, and mortality did not differ between groups. As-treated …