Association of clonal hematopoiesis of indeterminate potential with inflammatory gene expression in patients with severe degenerative aortic valve stenosis or chronic …
WT Abplanalp, S Mas-Peiro, S Cremer, D John… - JAMA …, 2020 - jamanetwork.com
Importance Cytokine release syndrome is a complication of coronavirus disease 2019.
Clinically, advanced age and cardiovascular comorbidities are the most important risk
factors. Objective To determine whether clonal hematopoiesis of indeterminate potential
(CHIP), an age-associated condition with excess cardiovascular risk defined as the
presence of an expanded, mutated somatic blood cell clone in persons without other
hematological abnormalities, may be associated with an inflammatory gene expression …
Clinically, advanced age and cardiovascular comorbidities are the most important risk
factors. Objective To determine whether clonal hematopoiesis of indeterminate potential
(CHIP), an age-associated condition with excess cardiovascular risk defined as the
presence of an expanded, mutated somatic blood cell clone in persons without other
hematological abnormalities, may be associated with an inflammatory gene expression …
