A multiplex polymerase chain reaction assay for antibiotic stewardship in suspected pneumonia
C Pickens, RG Wunderink, C Qi, H Mopuru… - … and infectious disease, 2020 - Elsevier
Background Multiplexed molecular rapid diagnostic tests (RDTs) may allow for rapid and
accurate diagnosis of the microbial etiology of pneumonia. However, little data are available
on multiplexed RDTs in pneumonia and their impact on clinical practice. Methods This
retrospective study analyzed 659 hospitalized patients for microbiological diagnosis of
suspected pneumonia. Results The overall sensitivity of the Unyvero LRT Panel was
85.7%(95% CI 82.3–88.7) and the overall specificity was 98.4%(95% CI 98.2–98.7) with a …
accurate diagnosis of the microbial etiology of pneumonia. However, little data are available
on multiplexed RDTs in pneumonia and their impact on clinical practice. Methods This
retrospective study analyzed 659 hospitalized patients for microbiological diagnosis of
suspected pneumonia. Results The overall sensitivity of the Unyvero LRT Panel was
85.7%(95% CI 82.3–88.7) and the overall specificity was 98.4%(95% CI 98.2–98.7) with a …