Clostridium perfringens toxin genotypes in the feces of healthy North Americans

RJ Carman, S Sayeed, J Li, CW Genheimer… - Anaerobe, 2008 - Elsevier
We investigated the frequency of Clostridium perfringens in the normal fecal flora of healthy
North Americans. About half of 43 subjects were colonized with C. perfringens at levels of∼
106cfu/g feces. Only type A strains were recovered. Spores sometimes outnumbered
vegetative cells. Several genotypes were found. Some donors carried two genotypes, some
only one. We found no alpha, beta2 or enterotoxin in the stools of any donors. Though some
isolates carried toxin genes (eg cpe and cpb2) on plasmids, we saw no indication that …