Cutaneous aging represents a complex situation in which at least two independent factors-
innate aging and solar exposure--contribute to the development of degenerative changes in
the dermis. The biochemical and ultrastructural evidence reviewed in this article indicates
that reduced collagen deposition, as a result of diminished collagen biosynthesis and
reduced proliferative capacity of the fibroblasts, could explain the development of dermal
atrophy and would relate to poor wound healing in the elderly. At the same time …