Serum antibody response to the gH/gL/pUL128–131 five-protein complex of human cytomegalovirus (HCMV) in primary and reactivated HCMV infections
E Genini, E Percivalle, A Sarasini, MG Revello… - Journal of clinical …, 2011 - Elsevier
BACKGROUND: Recently, a new human cytomegalovirus (HCMV) glycoprotein complex
has been identified and potentially proposed as a vaccine. OBJECTIVE: The aim of this
study was to determine whether the HCMV gH/gL/pUL128–pUL130–pUL131
(gH/gL/pUL128–131) 5-protein (pentameric) complex (which has been recently found to be
indispensable for the infection of endothelial and epithelial cells) is able to elicit a consistent
antibody response in both primary and reactivated HCMV infections. STUDY DESIGN: The …
has been identified and potentially proposed as a vaccine. OBJECTIVE: The aim of this
study was to determine whether the HCMV gH/gL/pUL128–pUL130–pUL131
(gH/gL/pUL128–131) 5-protein (pentameric) complex (which has been recently found to be
indispensable for the infection of endothelial and epithelial cells) is able to elicit a consistent
antibody response in both primary and reactivated HCMV infections. STUDY DESIGN: The …