[HTML][HTML] Pretransplant adaptive NKG2C+ NK cells protect against cytomegalovirus infection in kidney transplant recipients
M Ataya, D Redondo-Pachón, L Llinàs-Mallol… - American Journal of …, 2020 - Elsevier
Cytomegalovirus (CMV) infection constitutes a complication for kidney transplant recipients
(KTR) and CMV-specific T cells reduce the risk of viral replication in seropositive patients.
CMV promotes the adaptive differentiation and expansion of an NK cell subset, hallmarked
by expression of the CD94/NKG2C receptor with additional characteristic features. We
previously reported an association of pretransplant NKG2C+ NK cells with a reduced
incidence of CMV infection. We have strengthened the analysis in cryopreserved peripheral …
(KTR) and CMV-specific T cells reduce the risk of viral replication in seropositive patients.
CMV promotes the adaptive differentiation and expansion of an NK cell subset, hallmarked
by expression of the CD94/NKG2C receptor with additional characteristic features. We
previously reported an association of pretransplant NKG2C+ NK cells with a reduced
incidence of CMV infection. We have strengthened the analysis in cryopreserved peripheral …
