[HTML][HTML] Clinical trial of the pan-caspase inhibitor, IDN-6556, in human liver preservation injury
ES Baskin-Bey, K Washburn, S Feng… - American Journal of …, 2007 - Elsevier
Cold ischemia/warm reperfusion (CI/WR) injury remains a problem in liver transplantation.
The aim of the current study was to assess the utility of the pan-caspase inhibitor IDN-6556
on CI/WR injury during human liver transplantation. This report is a post hoc analysis of a
Phase II, multi-center, randomized, placebo-controlled, double-blinded, parallel group study.
infjects were assigned to four treatment groups: Group 1 (Organ storage/flush: Placebo—
Recipient: Placebo); Group 2 (Organ storage/flush: 15 μg/mL—Recipient: Placebo); Group 3 …
The aim of the current study was to assess the utility of the pan-caspase inhibitor IDN-6556
on CI/WR injury during human liver transplantation. This report is a post hoc analysis of a
Phase II, multi-center, randomized, placebo-controlled, double-blinded, parallel group study.
infjects were assigned to four treatment groups: Group 1 (Organ storage/flush: Placebo—
Recipient: Placebo); Group 2 (Organ storage/flush: 15 μg/mL—Recipient: Placebo); Group 3 …