Immune reconstitution/immunocompetence in recipients of kidney plus hematopoietic stem/facilitating cell transplants
JR Leventhal, MJ Elliott, ES Yolcu, LD Bozulic… - …, 2015 - journals.lww.com
Transplantation, 2015•journals.lww.com
MATERIALS AND METHODS All protocols are approved by the Northwestern University
(NWU) and University of Louisville Institutional Review Boards and the FDA (IDE 13947).
Informed consent was obtained for all donors and recipients. Subjects met institutional
criteria as suitable living transplant donors and recipients as described. 4, 13 FCRx
Preparation At least 2 weeks before the renal transplantation, donors were mobilized with G-
CSF (10 μg/kg twice daily), and apheresis was performed on day 4 or 5 of treatment. The …
(NWU) and University of Louisville Institutional Review Boards and the FDA (IDE 13947).
Informed consent was obtained for all donors and recipients. Subjects met institutional
criteria as suitable living transplant donors and recipients as described. 4, 13 FCRx
Preparation At least 2 weeks before the renal transplantation, donors were mobilized with G-
CSF (10 μg/kg twice daily), and apheresis was performed on day 4 or 5 of treatment. The …
MATERIALS AND METHODS All protocols are approved by the Northwestern University (NWU) and University of Louisville Institutional Review Boards and the FDA (IDE 13947). Informed consent was obtained for all donors and recipients. Subjects met institutional criteria as suitable living transplant donors and recipients as described. 4, 13
FCRx Preparation At least 2 weeks before the renal transplantation, donors were mobilized with G-CSF (10 μg/kg twice daily), and apheresis was performed on day 4 or 5 of treatment. The product was immediately transported by courier in a controlled temperature container to Louisville and processed by a proprietary approach using the CliniMACS (Miltenyi Biotec, Auburn, CA) to remove mature donor GVHD-producing
Lippincott Williams & Wilkins