Angiogenesis and scar formation in healing wounds

LA DiPietro - Current opinion in rheumatology, 2013 - journals.lww.com
Current opinion in rheumatology, 2013journals.lww.com
One well described feature of wound healing is the ingrowth of new capillaries or
angiogenesis. At its peak, the capillary content in healing wounds may reach three or more
times that of normal uninjured tissue. This new vasculature is required to restore
oxygenation and allow the growth of new tissue to fill the wound space. This review
examines the assumption that a capillary content in excess of normal density is essential for
adequate healing.
One well described feature of wound healing is the ingrowth of new capillaries or angiogenesis. At its peak, the capillary content in healing wounds may reach three or more times that of normal uninjured tissue. This new vasculature is required to restore oxygenation and allow the growth of new tissue to fill the wound space. This review examines the assumption that a capillary content in excess of normal density is essential for adequate healing.
Lippincott Williams & Wilkins