Macro-architecture of basal ganglia loops with the cerebral cortex: use of rabies virus to reveal multisynaptic circuits
RM Kelly, PL Strick - Progress in brain research, 2004 - Elsevier
We have used retrograde transneuronal transport of rabies virus to examine basal ganglia
connections with the cerebral cortex. We injected rabies into the primary motor cortex (M1)
or into Area 46 of cebus monkeys. A 4-day survival time was long enough to allow transport
of rabies from the injection site to 'third-order'neurons in the basal ganglia. After either M1 or
Area 46 injections, third-order neurons were found in the external segment of the globus
pallidus (GPe), striatum and subthalamic nucleus (STN). In each of these nuclei, the third …
connections with the cerebral cortex. We injected rabies into the primary motor cortex (M1)
or into Area 46 of cebus monkeys. A 4-day survival time was long enough to allow transport
of rabies from the injection site to 'third-order'neurons in the basal ganglia. After either M1 or
Area 46 injections, third-order neurons were found in the external segment of the globus
pallidus (GPe), striatum and subthalamic nucleus (STN). In each of these nuclei, the third …
