Pathology of postprimary tuberculosis in humans and mice: contradiction of long-held beliefs

RL Hunter, C Jagannath, JK Actor - Tuberculosis, 2007 - Elsevier
Tuberculosis remains one of the world's leading infectious causes of death. Approximately
80% of all disease is due to postprimary (secondary) tuberculosis in the lung. Unfortunately,
tissues of developing lesions are seldom available and there are no recognized models of
postprimary tuberculosis. In the preantibiotic era when tissues were more abundant, several
investigators described early postprimary tuberculosis as a lipid pneumonia quite different
from the caseating granulomas commonly described today. We used histopathologic …